Small children. Promethazine/codeine shouldn't be used in any boy or girl young than 12 many years of age or in a youngster more youthful than eighteen a long time of age following a operation to remove their tonsils or adenoids (tonsillectomy and/or adenoidectomy). Sluggish or shallow breathing that may result in Dying might come about.
Use an accurate measuring machine to evaluate your dose of promethazine/codeine. A residence spoon just isn't an correct measuring gadget and will lead to you to definitely choose the incorrect dose. Request your pharmacist to advise an ideal measuring product.
Promethazine hydrochloride and codeine phosphate should be presented into a Expecting female provided that Obviously needed.
The phosphate salt of codeine takes place as white, needle-shaped crystals or white crystalline powder. Codeine phosphate is freely soluble in h2o and a little bit soluble in Alcoholic beverages. The molecular weight is 406.37. Its molecular method is C18H21NO3•H3PO4 • ½ H2O, and it has the next chemical structure.
If you're using sustained-launch tablets or capsules, swallow the medication full. Tend not to crush, chew, or split the tablets or capsules. Doing so can destroy the long motion of your drug and should boost Unintended effects.
Promethazine is perfectly absorbed from the gastrointestinal tract. Scientific consequences are apparent within 20 minutes following oral administration and generally previous 4 to 6 hours, although They might persist as long as 12 hrs.
Clearance can be lessened as well as the metabolites may well accumulate to much greater plasma concentrations in clients with renal failure when compared to clients with regular renal functionality.
Human Knowledge Revealed data from more info scenario-Handle and observational studies on codeine use through pregnancy are inconsistent in their results. Some studies of codeine exposure confirmed an elevated possibility of All round congenital malformations while some didn't.
Keep at space temperature away from gentle and moisture. Do not keep in the bathroom. Do not freeze liquid forms of this medication. Continue to keep all prescription drugs from youngsters and Animals.
Codeine is amongst the Obviously developing phenanthrene alkaloids of opium derived from your opium poppy; it is assessed pharmacologically being a narcotic analgesic.
INDICATIONS here AND Utilization Promethazine HCl and Codeine Phosphate Oral Resolution is a combination of codeine, an opioid agonist; and promethazine, a phenothiazine, indicated to the short term reduction of more info cough and upper respiratory symptoms associated with allergy or the common chilly in clients 18 a long time of age and older. (one)
常見之不良反應有：瘙癢、噁心、嘔吐、昏睡、口乾、瞳孔縮小、姿態性低血壓（orthostatic hypotension）、小便不暢、便秘。
Codeine has superior antitussive action, Hi-Tech promethazine syrup Though under that of morphine at equivalent doses. It is actually Utilized in preference to morphine, simply because Unwanted side effects are rare at the standard antitussive dose of codeine.
One example is, several reported conditions of Demise occurred get more info during the put up-operative period following tonsillectomy and/or adenoidectomy, and plenty of of the children had proof of becoming extremely-rapid metabolizers of codeine. On top of that, youngsters with obstructive slumber apnea who are dealt with with codeine for post-tonsillectomy and/or adenoidectomy soreness may be significantly sensitive to its respiratory depressant influence. As a result of possibility of lifestyle-threatening respiratory despair and Demise: